Wednesday, April 30, 2025

Could Sam-e be helpful for my dogs?

I have 2 shepherds I'm thinking about giving Sam-e to, because it's really good for the liver and works as an antidepressant. I've used it before and can say it really does boost mood. I almost always get it from Costco, where it comes on sale at least twice a year. 

I am thinking of giving it to my dog Kali, who has tumors i am trying to shrink. I learned that things that improve liver health also tend to boost your mood. I also want to give this to my dog Fafi, who is pretty neurotic and has a lot of anxiety. I think her condition will improve when I can spend more time with her, but right now I'm dealing with some issues that really limit my time. 

In my research today in Sam-e, I looked for reviews from people who said they gave it to their dog. Since I looked it up, I thought it might be worth posting here, for anyone else who might want to see this. A few people said it helped their dogs who had depression. 

Overall, the reviews are really good. One person complained it is a laxative and gave it a bad review, please do your own research on that, I haven't verified this in any way, just know it worked great for me, and intend to give it to my dogs as soon as I can afford it. 


Nature Made SAM-e 200 mg Complete

Dietary Supplement for Mood Support, 

60 Tablets, 30 Day Supply

From the United States



  • 117 people found this helpful
  • Reviewed in the United States on December 9, 2013
    We use this supplement for our 13-year old dog (pit/boxer mix; 50 lbs) who developed liver issues and had two abnormally high liver enzymes in her blood work. She suffered from unquenchable thirst and ravenous hunger. She did not have Cushing's Disease. We were freezing her water and at wits end watching a great dog suffer. After using this and milk thistle for three months, one of her enzymes return to normal range and the other was stable. Her symptoms completely abated. Why I recommend this product over other brands (we tried many) is that we got very consistent results from only this brand. When on the others, the symptoms would return and we had to try giving her additional dosages or change back to this brand to make her symptoms go away. It appears that this brand has good quality controls. We have been using this brand exclusively for two years and have had good/great results. This supplement is suppose to "restore a healthy mood" in people, I know that it has made me incredibly happy to see my dog feel better and be symptom free.
    6 people found this helpful
    Report

  • Reviewed in the United States on September 27, 2016
    I heard about Sam-e when it was recommended for my dog and I did some research online. Long story short, I started taking it myself as well. I'm a physician and wasn't sure what to expect. TWO EFFECTS
    1) My chronic low grade depression has completely resolved. Its like I have a new positive outlook on life. NO other medicine has ever helped me with this issue.
    2) This drug has improved my libido from a life long 1/10 to a 10/10, and I'm over 60. It is literally a miracle as far as I am concerned.

    The only negative effect if you want to call it that is I now just sleep about 5 hours a night. No insomnia, just rested and ready to go after 5 hours.

    The above is all true and written by someone who considers 99.999% of all supplements total BS.
    46 people found this helpful
    Thank you for your feedback.
     
    Report
  • Reviewed in the United States on August 1, 2017
    Great quality, consistent and easy to open foil packs. So tired of mg strengths exceeding what is needed to achieve results or packaging that arthritic hands cannot open without scissors. I know the quality of product from Nature Made. I administer one tablet to my senior dog first thing in the morning, before any food. It has helped his liver but the addition of Milk Thistle twice a day was the clincher. To help with any stomach upset, he also gets Pepcid A/C twice a day too, and once a day, he gets Trinfac-B, which boosts his energy level. The combo of supplements and medication has allowed us to beat back Father Time for over a year. Savoring every day and thankful for this quality product.
    46 people found this helpful
    Thank you for your feedback.
     
    Report
  • Reviewed in the United States on May 29, 2022
    I order as liver supplement for my 60 lb dog. Wish they were smaller so easier to swallow. I put in small amount of cheese.
    3 people found this helpful
    Report
  • Reviewed in the United States on February 21, 2014
    I have a 10 year old Boston Terrier who suffers from early symptoms of Alzheimers which has quite an impact on his mood. When I took him to our veterinarian, she recommended SAM-e 400mg tablets to boost his mood and hopefully give him a much happier outlook on life. I give him half of a tablet, once per day as recommended by the vet and so far he has wanted to run around, play, and get lots of attention (which is something he NEVER wanted to do before)! I highly recommend this if your dog is of senior age and experiencing the same symptoms as my dog was, but before you try this, you MUST talk to your veterinarian prior to giving your dog this because there could be other underlying issues your dog may have that are impacting his or her mood.
    15 people found this helpful
    Report
  • Reviewed in the United States on May 25, 2013
    I ordered SAM-e per recommendation by our vet. Our older dog (she is 14 now) began to exhibit signs of mental deterioration (confusion, barking endlessly, etc.) so we decided to give these a shot before taking her to a neurologist. Not only has she improved mentally, but she seems to be more active and spry. She is a dachshund, so we worry about joint pain, and ever since we started giving her these tablets, she seems like the dog she was two years ago. While they were not a cure all, and she still sometimes gets confused (probably more now because of her limited vision than mental clarity), they really worked wonders for her. We are very happy with the results, as we are confident that we will have more time with our wonderful baby.
    2 people found this helpful
    Report
  • Reviewed in the United States on July 13, 2016
    Actually, I give 200 mg SAM-e to both my dogs--one a day about an hour before dinner. A few years ago, my now 14-year old terrier mix rescue had kidney and bladder stones, and also felt he may have a liver issue. The Vet put him on Denamarin and a urinary prescription diet. Then a Vet specialist she sent me to said the one ingredient he really needs in the Denamarin is in SAM-e, and it's much less expensive. I've been giving this to him ever since, and also give it to my now 16-year old terrier mix rescue. I LOVE my adopted furry children!
    Customer image
    19 people found this helpful
    Report
  • Reviewed in the United States on June 11, 2018
    I use this for my German Shepherd. She was depressed because my other dog died. The vet recommended I give her this and has certainly helped.

    Not only does it help with depression but it has joint support. Anyone who knows about German Shepherds knows that is a excellent addition to the product!
    3 people found this helpful
    Thank you for your feedback.
     
    Report

From the United States





From the United States